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Patients and providers can report side effects to the FDA MedWatch program, which collects safety data

This is information, not medical advice

PLoS ONE 5 , e9085 (2010)

Preclinical studies indicate that metformin promotes M2 macrophage polarization through STAT6 activation, which facilitates tissue repair and attenuates TGF-1-mediated renal fibrosis (109)

There hasnt been a breakthrough in medications with such tremendous public health relevance related to chronic disease prevention since the advent of statins in 1986, which revolutionized treatment of high cholesterol, and protease inhibitors in 1996, which turned HIV from a death sentence to a chronic, manageable illness

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