Fenretinide - CAS# 65646-68-6 127 4SC-202 was used at 10µM

4SC-202 was used at 10µM final concentration in various in vitro assays

Zajac-Kaye M

(2008) J Med Chem

5 day) potently and selectively inhibits IL-17 and IL-22 levels

Vesnarinone improves ventricular performance most in patients with the worst degree of heart failure

Fenretinide - CAS# 65646-68-6 127 4SC-202 was used at 10µMFenretinide, CAS No. 65646 68 6, is an orally active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis associated growth factors and their receptors and exhibits retinoid