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If this dilation of lymphatic vessels is consistent with lymphostatic decompensation (failure of lymphatic vessel function) in lipedema as the authors suggest, then salt should be found in the skin of women with lipedema as lymphatic vessels regulate Na+, Cl and water in the skin, where reduced lymphatic vessel numbers are paralleled by increased blood pressure (82)

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IL-6 is very beneficial in the wound healing process at the beginning of injury that stimulates epithelial proliferation

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It means that many patients do not feel the urge to defecate, especially the elderly, who they often have a reduced tone of the colon and anal sphincter and then there must be the inhibitory reflex of the anal sphincters