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Along these lines, HFD-fed NCC KO mice showed exacerbated body weight gain, glucose intolerance and insulin resistance relative to chow fed mice (Zhang et al., 2022a

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The hypothesis of the link between PLC, inflammation and cancer has been also confirmed by Yang et al., who showed that knockdown of PLC by shRNA decreased not only PLC expression itself, but also the expression of inflammatory cytokines IL-6, TNF-, IL-2 and inflammation-associated genes TLR-4, MyD88 and phosphorylated STAT-3 [58]

Our findings also underscore the crucial role of central redox mechanisms, particularly in the mPFC, in mediating the pathophysiological effects of THC

Semaglutide has since emerged as the preferred option for weight loss due to its superior results compared to liraglutide