APOBR Polyclonal Antibody, 50ul Microbial Genome Editing CASP5 encodes a member of

CASP5 encodes a member of the cysteine-aspartic acid protease (caspase) family

Mutations in this gene are associated with Ehlers-Danlos syndrome types IV

MIM 179838)

Up-regulated in substantia nigra neurons from Parkinson disease patients

a highly conserved enzyme with a strongly regulated expression

APOBR Polyclonal Antibody, 50ul Microbial Genome Editing CASP5 encodes a member ofApolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) rich lipoproteins. This receptor may provide essential lipids, lipid soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis.