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To understand the role of exogenous IGF-1 and gene transfer of IGF-1 in stress-induced hepatocyte premature aging, in vivo, IGF-1 gene transferred to CCl 4 -induced rat models with lentivirus vectors to overexpress intrahepatic IGF-1

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While there was a numerical reduction in the incidence of MI (aHR, 0.88

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Some research also suggests potential benefits for conditions such as fatty liver disease and obstructive sleep apnea