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More pointedly, a 24month retrospective cohort study in older adults with type 2 diabetes reported that semaglutide use was associated with muscle loss and functional decline, particularly at higher doses and in patients who already had sarcopenia

[ [PMID: 36998152] [ [PMID: 38230324] [ [PMID: 35838946] [ [PMID: 35873937] [ [PMID: 33964002] [ [PMID: 28941314] [ [PMID: 10605628] [ [PMID: 17928588] [ [PMID: 34815532] versus placebo when added to intensive behavioral therapy