Tie-1 Polyclonal Antibody, 100ul Reagent Reservoirs The encoded protein may play
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Tie-1 Polyclonal Antibody, 100ul Reagent Reservoirs The encoded protein may playTIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth
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