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It is a benign monoclonal tumor of the uterine smooth muscle cells

Because it competes at the nicotinamide substrate site rather than the SAM cofactor site, it is also used as the substrate-competitive reference compound against which bisubstrate and covalent NNMT inhibitors are benchmarked

Interestingly, the activity of such plasma membrane oxidase systems has been demonstrated to increase in Rho O cells that lack functional mitochondria [51, 52]

They vary in potency, administration and length, of course

Kambayashi R, Goto A, Takahara A, Saito H, Izumi-Nakaseko H, Takei Y, Akie Y, Hori M, Sugiyama A

Oxidative stress in allergic and inflammatory skin diseases