NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody, 20ul PCR Series 3) associated with gonadal dysgenesis

3) associated with gonadal dysgenesis and XY sex reversal

CD9 encodes a member of the transmembrane 4 superfamily

a type II transmembrane TNF superfamily member with high identity to TNF in its extracellular portion

This gene is a candidate gene for Hirschsprung disease

The protein is named for Strumpell disease

NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody, 20ul PCR Series 3) associated with gonadal dysgenesisThis gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial