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To view a copy of this licence, visit About this article Cite this article Godlewska, B.R., Sylvester, A.L., Emir, U.E

This reaction requires -ketoglutarate, oxygen, and ascorbate (vitamin C) as cofactors and takes place in the mitochondria

This unceremonious amputation requires special enzymes called decarboxylases (fancy word for enzymes that chop off carboxyl groups)

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The SURMOUNT-OSA trial put a spotlight on this progress, showing that a pharmacological approach can drastically cut OSA severity